This test checks for common mutations in the MTHFR gene (C677T and A1298C), which can affect how your body processes folate and homocysteine—impacting areas like energy, mood, heart health, and fertility.
Your results delivered as a complete pathology report, with reference ranges and clinical context for every marker. Easy to read yourself or hand straight to your GP.
The same pathology report format used by hospitals and GPs across Australia.
Every result is shown alongside the normal range. Abnormal results are highlighted in red so you spot them straight away.
Delivered privately within 24-48 hours of testing. Yours to keep, share or print.
See at a glance which markers are healthy and which need attention.
Calculated free testosterone is below the lower reference limit. May be associated with symptoms of low testosterone including fatigue, low libido, and reduced energy.
The MTHFR enzyme drives methylation, the biochemical process behind DNA repair, neurotransmitter production, detoxification and cardiovascular health. C677T and A1298C variants can reduce its activity by 30-70%.
Reduced MTHFR activity means homocysteine builds up. Elevated homocysteine is independently linked to heart attack, stroke, dementia and cognitive decline. Knowing your MTHFR status reveals whether genetics is contributing.
MTHFR variants are linked to recurrent miscarriage, neural tube defects and pregnancy complications. Couples with unexplained fertility issues often carry these variants. Knowing your status changes the folate strategy.
With MTHFR variants, regular folic acid is poorly converted. Methylfolate (active L-5-MTHF) is the bioavailable form. The test reveals which form of folate, B12 and B vitamins actually work for your biology.
MTHFR tells you the genetics. Homocysteine tells you whether it is currently affecting your body. Tested together, they reveal exactly what is happening with your methylation right now.
MTHFR variants are genetic and do not change. A single test gives you lifetime information for B vitamin supplementation, fertility decisions and cardiovascular risk management. Walk in to any of our 3,300+ collection centres, results in 24-48 hours.
Australia's easiest blood test
Step one
Order your blood test
Choose from 200+ blood tests or build your own. Once purchased, you'll get an instant pathology request form delivered to your inbox as a PDF, ready for use.
Instant pathology request formStep two
Walk in to collect your sample
Take your pathology request form to any of our 3,300+ partner collection centres across Australia. No need to book, just walk in and get your sample collected.
3,300+ collection centresStep three
Receive your results
Your results are reviewed by our AHPRA-registered doctors and sent privately to your email or SMS, usually within 24-48 hours.
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This genetic test identifies two common variations in the MTHFR gene — C677T and A1298C — which can affect how efficiently your body processes folate, vitamin B12, and homocysteine. These mutations can influence methylation, a key biological process involved in energy production, detoxification, mood regulation, and cardiovascular health.
Testing for both variants helps determine whether your methylation pathways are functioning optimally or if you may be at increased risk for elevated homocysteine levels, fatigue, fertility issues, or mood imbalances. It’s particularly useful for individuals with a family history of heart disease, recurrent miscarriage, or nutrient deficiencies. Understanding your MTHFR status allows for more personalised dietary and supplement strategies to support your long-term health and wellbeing.
C677T Mutation: Detects a common change in the MTHFR gene that can reduce enzyme activity and affect how your body processes folate and homocysteine.
A1298C Mutation: Identifies another MTHFR gene variation that may impact folate metabolism and, when combined with C677T, can influence methylation and overall metabolic health.
1. Receive your referral instantly after purchase
2. Quick blood test at your local collection centre
3. Results to your inbox within 1-2 days
